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Invitrogen™ FANCD2 Polyclonal Antibody
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Codice prodotto. 11555313
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Quantità:
50 μL
Dimensione della confezione:
50µL
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Codice prodotto. Quantità unitSize
11555313 50 μL 50µL
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Codice prodotto. 11555313 Fornitore Invitrogen™ N. del fornitore PA116548

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Descrizione

Rabbit Polyclonal Antibody

In Western blot, this antibody should recognize a band at ~166 kDa (post-translationally modified form). Additional bands may be seen at lower molecular weights. In immunofluorescence, this has been tested in human MMC and IR-treated MEF cells.Suggested positive control: Hela whole cell extract.

FANCD2 (Fanconi anemia group D2 protein) is required for maintenance of chromosomal stability. It promotes accurate and efficient pairing of homologs during meiosis. FANCD2 is involved in the repair of DNA double-stranded breaks, both by homologous recombination and single-stranded annealing. It is required for the targeting/stabilization of BLM to non-centromeric abnormal structures induced by replicative stress. FANCD2 promotes BRCA2/FANCD1 loading onto damaged chromatin. Defects in the FANCD2 gene result in Fanconi anemia complementation group D2. This disorder affects all bone marrow elements resulting in anemia, leukopenia, and thrombopenia.
TRUSTED_SUSTAINABILITY

Specifica

Antigene FANCD2
Applicazioni ChIP Assay, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 0.05% sodium azide
Gene FANCD2
N. accesso geni Q6IV68, Q80V62, Q9BXW9
Alias gene 2410150O07Rik; AU015151; BB137857; DKFZp762A223; FA4; FACD; FACD2; FAD; FAD2; FA-D2; FANCD; FANCD2; Fanconi anemia complementation group D2; Fanconi anemia D2 protein; Fanconi anemia group D2 protein; Fanconi anemia group D2 protein homolog; Fanconi anemia, complementation group D2; FLJ23826; Protein FACD2
Simboli geni FANCD2
Specie ospite Rabbit
Immunogeno Human FANCD2 fusion protein (N-terminal fragment).
Metodo di purificazione Antigen affinity chromatography
Quantità 50 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 211651, 2177, 312641, 394241, 484659
Target Species Human, Mouse, Rat, Canine, Monkey, Avian, Zebrafish, Marsupial
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Forma Liquid
Isotype IgG
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