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Fedratinib, MedChemExpress

Codice prodotto. 16443958
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Quantità:
5 mg
10 mg
100 mg
Dimensione della confezione:
100mg
10mg
5mg
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Product Code. 16443958

Brand: Medchem Express HY10409

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Description

MedChemExpress Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.

Fedratinib (TG-101348) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor with IC50s of 3 nM for both JAK2 and JAK2V617F kinase. Fedratinib shows 35- and 334-fold selectivity over JAK1 and JAK3, respectively. Fedratinib induces cancer cell apoptosis and has the potential for myeloproliferative disorders research.

Specifications

Materiale o nome chimico Fedratinib
CAS 936091-26-8
Colore Light Nude
Note sul grado di purezza Research
Formula molecolare C27H36N6O3S
Quantità 10 mg
Sinonimo TG-101348 SAR 302503
Informazioni di solubilità DMSO : 125 mg/mL (238.24 mM; Need ultrasonic)
SMILES O=S(C1=CC=CC(NC2=NC(NC3=CC=C(C=C3)OCCN4CCCC4)=NC=C2C)=C1)(NC(C)(C)C)=O
Molecular Weight (g/mol) 524.68
Peso formulazione 524.68
Percent Purity 98.02%
Grado Research
Forma fisica Powder
Da utilizzare con (applicazione) Cancer-Kinase/protease
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Research purposes only

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