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Fumonisin B1, 96%

Codice prodotto. 10741361 Sfoglia Tutto Thermo Scientific Chemicals Prodotti
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Codice prodotto. 10741361 Fornitore Thermo Scientific Acros N. del fornitore 328250010
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Description

Fumonisin, CAS # 116355-83-0, also known as Macrofusine, is a cell permeable mycotoxin that is an inhibitor of sphingosine N-acetyl transferase. | CAS: 116355-83-0 | C34H59NO15 | 721.8 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Fumonisin is a fungal metabolite that is a cell permeable mycotoxin that can halt sphingolipid biosynthesis by inhibiting sphingosine N-acetyl transferase

Applications

• It can potently inhibit sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases

• It is also a protein serine and threonine phosphatase inhibitor

• It can selectively inhibit sphingomyelin biosynthesis in neuronal cells

TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 116355-83-0
Formula molecolare C34H59NO15
Molecular Weight (g/mol) 721.8
Numero MDL MFCD00133349
InChI Key UVBUBMSSQKOIBE-UWCNXKJPSA-N
Sinonimo macrofusine, fumonisin b1, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,4r,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,11r,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid
PubChem CID 16760030
IUPAC Name (2S)-2-[2-[(5R,6R,7S,9S,11R,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-11,16,18-trihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
SMILES CCCCC(C)C(C(CC(C)CC(CCCCC(CC(C(C)N)O)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O

Specifications

Materiale o nome chimico Fumonisin B1
Colore Tan to White
Analisi elementare 55.00 to 58.00%C, 1.60 to 2.20%N
Intervallo percentuale saggio 95% min. (HPLC)
Quantità 1 mg
Indice di Merck 15, 4318
Informazioni di solubilità Solubility in water: soluble. Other solubilities: soluble in methanol,acetonitrile
Peso formulazione 721.8
Percent Purity 96%
Forma fisica Powder

Safety and Handling

compliance-icons
Product Identifier
  • Fumonisin B1
 Signal Word
  • Attenzione
 Hazard Category
  • cancerogenicità Categoria 2
 Hazard Statement
  • H351-Sospettato di provocare il cancro.
 Precautionary Statement
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
SDS

RUO – Research Use Only

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