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Fumonisin B2, 96+%

Product Code. 10440931 Shop All Thermo Scientific Chemicals Products
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Product Code. 10440931 Supplier Thermo Scientific Acros Supplier No. 328260010
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Description

Fumonisin B2, CAS # 116355-84-1, is a diester of tricarballylic acid and is isolated from Fusarium. | CAS: 116355-84-1 | C34H59NO14·3H2O | 759.9 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Fumonisin B2 is a fumonisin mycotoxin produced by the fungus Fusarium
  • Fumonisin B2 is a structural analog of fumonisin B1 but it is more cytotoxic than B1 and can inhibit sphinganine-N-acetyltransferase (ceramide synthase)

Applications

  • In vitro and in vivo studies have shown Fumonisin B2 can induce apoptosis
  • It can inhibit de novo sphingolipid biosynthesis
  • It is also considered an Aspergillus metabolite
  • It shows cytotoxicity against a panel of seven rat hepatoma cell lines, and MDCK cell line
  • It induces hepatocyte nodule formation, a marker of cancer initiation, in rats
TRUSTED_SUSTAINABILITY

Specifications

Materiale o nome chimico Fumonisin B2
CAS 116355-84-1
Intervallo percentuale saggio 96+%
Formula molecolare C34H59NO14·3H2O
Quantità 1 mg
Sinonimo fumonisin b2, 2r,2'r-1,2,3-propanetricarboxylic acid 1,1'-1s,2r-1-2s,9r,11s,12s-12-amino-4,9,11-trihydroxy-2-methyltridecyl-2-1r-1-methylpentyl-1,2-ethanediyl ester, 2s-2-2-5r,6r,7s,9s,16r,18s,19s-19-amino-6-3r-3,4-dicarboxybutanoyl oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl oxy-2-oxoethyl butanedioic acid
Informazioni di solubilità Solubility in water: .. Other solubilities: soluble in methanol
InChI Key UXDPXZQHTDAXOZ-FWPUDPCBSA-N
SMILES CCCCC(C)C(C(CC(C)CCCCCCC(CC(C(C)N)O)O)OC(=O)CC(CC(=O)O)C(=O)O)OC(=O)CC(CC(=O)O)C(=O)O
IUPAC Name (2S)-2-[2-[(5R,6R,7S,9S,16R,18S,19S)-19-amino-6-[(3R)-3,4-dicarboxybutanoyl]oxy-16,18-dihydroxy-5,9-dimethylicosan-7-yl]oxy-2-oxoethyl]butanedioic acid
Molecular Weight (g/mol) 759.9
PubChem CID 71317007
Peso formulazione 759.9
Percent Purity 96+%
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Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • Fumonisin B2
 Signal Word
  • Pericolo
 Hazard Category
  • Tossicità acuta Categoria 1
  • cancerogenicità Categoria 2
  • Lesione oculare grave/irritazione oculare Categoria 2
  • Corrosione/irritazione della pelle Categoria 2
  • Tossicità specifica per organi bersaglio (esposizione singola) Categoria 3
 Hazard Statement
  • H310-Letale per contatto con la pelle.
  • H330-Letale se inalato.
  • H315-Provoca irritazione cutanea.
  • H319-Provoca grave irritazione oculare.
  • H351-Sospettato di provocare il cancro.
  • H335-Può irritare le vie respiratorie.
  • H300-Letale se ingerito.
 Precautionary Statement
  • P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P310-IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI/un medico
  • P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
  • P310-Contattare immediatamente un CENTRO ANTIVELENI/un medico .
  • P361-Togliere immediatamente tutti gli indumenti contaminati.
SDS

RUO – Research Use Only

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