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Gibco™ HepaRG™ Cells, Cryopreserved

Codice prodotto. 13496438 Sfoglia Tutto Gibco Prodotti
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Codice prodotto. 13496438 Fornitore Gibco™ N. del fornitore HPRGC10
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Descrizione

The HepaRG™ Cells, Cryopreserved cell line is an immortalized hepatic cell line that retains many characteristics of primary human hepatocytes.

The HepaRG™ cell line is an immortalized hepatic cell line that retains many characteristics of primary human hepatocytes. HepaRG™ cells are terminally differentiated and provided in a convenient cryopreserved format. For scientists who need reproducible metabolism data, HepaRG™ cells are an in vitro tool that provides reproducible results in a metabolically complete and scalable system.

  • Obtain biologically relevant results from a metabolically complete system
  • Assess the drug-drug interaction potential of your compound
  • Experience reproducible results from a single population of cells

Biologically Relevant

HepaRG™ cells exhibit many characteristics of primary human hepatocytes including morphology, expression of key metabolic enzymes, expression of nuclear receptors, and drug transporters. Unlike HepG2 and Fa2N-4 cells, HepaRG™ cells have high P450 activity and complete expression of all nuclear receptors.

Predict Metabolism-based Drug-drug Interaction

HepaRG™ cells respond to prototypical P450 inducers and inhibitors to the same extent as primary hepatocytes, allowing HepaRG™ cells to be used to evaluate potential drug-drug interactions.

Infinitely Reproducible

HepaRG™ cells exhibit many characteristics of primary human hepatocytes and are essentially a single donor. These features allow users to obtain physiological relevant results for metabolism-based drug-drug interactions without the concern of donor variability and limited lot sizes that come with relying on donor tissue. (Note: The cells we provide are terminally differentiated).

HepaRG™ is a trademark of BioPredic International.

TRUSTED_SUSTAINABILITY

Specifica

Content And Storage 1 vial, store in cryostorage dewar or -135°C freezer
Age Adult
Linea cellulare HepaRG
Tipo di cellula Hepatocytes
Culture Type Hepatocyte Cell Culture
Forma Cryopreserved
Sesso Female
Specie Human
Tissue Liver
Donor Source Single Donor
N. di celle 10 x 106
Product Type Hepatocytes
Quantità 1 vial
Shipping Condition Dry Ice
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For Research Use Only. Not for use in diagnostic procedures.

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