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Histamine dihydrochloride, 98+%

Codice prodotto. 11387276
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25 g
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11387276 5 g 5g
11397276 25 g 25g
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Codice prodotto. 11387276 Fornitore Thermo Scientific Alfa Aesar N. del fornitore L09198.06
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Descrizione

CAS: 56-92-8 | C5H11Cl2N3 | 184.06 g/mol

Histamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Histamine dihydrochloride has been shown to activate nitric oxide synthetase and suppress or inhibit the generation of reactive oxygen species (ROS). Inhibition of ROS by histamine dihydrochloride allows activation of T cells and NK cells by IL-2. In a rat model, histamine dihydrochloride suppressed ROS generated by Kupffer cells through the H2 histamine receptor. It is a potent vasodilator and endogenous histamine receptor agonist.

Solubility
Very soluble in water and methanol. Soluble in ethanol.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents. Store away from oxidizing agents. Store at 4°C.
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 56-92-8
Formula molecolare C5H11Cl2N3
Molecular Weight (g/mol) 184.06
Numero MDL MFCD00012703
InChI Key PPZMYIBUHIPZOS-UHFFFAOYSA-N
Sinonimo histamine dihydrochloride, histamine 2hcl, 2-1h-imidazol-4-yl ethanamine dihydrochloride, 1h-imidazole-4-ethanamine dihydrochloride, 1h-imidazole-4-ethanamine, dihydrochloride, peremin, ceplene, 2-1h-imidazol-4-yl ethylamine dihydrochloride, 2-4-imidazolyl ethylamine dihydrochloride, histaminedium dichloride
PubChem CID 5818
IUPAC Name 2-(1H-imidazol-5-yl)ethanamine;dihydrochloride
SMILES [H+].[H+].[Cl-].[Cl-].NCCC1=CN=CN1

Specifica

Materiale o nome chimico Histamine dihydrochloride
Punto di fusione 245°C to 249°C
Quantità 5 g
Beilstein 3624116
Indice di Merck 14,4719
Informazioni di solubilità Very soluble in water and methanol. Soluble in ethanol.
Peso formulazione 184.07
Percent Purity ≥98%

RUO – Research Use Only

Titolo del prodotto
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