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HIV1 gp120 Polyclonal Antibody, Invitrogen™
Goat Polyclonal Antibody
Marca: Invitrogen PA520584
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Descrizione
PA5-20584 can be used with blocking peptide PEP-0704.
Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.
Specifica
| HIV1 gp120 | |
| Polyclonal | |
| Unconjugated | |
| HIV Glycoprotein 120; HIV-1 Glycoprotein 120; Human immunodeficiency virus | |
| 15 amino acids from near the center of gp120. | |
| 100 μg | |
| Primary | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Western Blot | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Goat | |
| Antigen affinity chromatography | |
| RUO | |
| Virus | |
| Antibody | |
| IgG |
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