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ACROBiosystems Human LGR5 / GPR49 protein, His Tag

Marca:  ACROBiosystems LG5-H52H3-100ug

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 17296290

  • 418.61€ / 100µg

Spedizione stimata: 16-02-2023
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Descrizione

Descrizione

LGR5 (also known as GPR49) is a seven-transmembrane protein of the class A Rhodopsin-like family of GPCRs. LGR5 and LGR4 bind the R-spondins with high affinity and mediate the potentiation of Wnt/β-catenin signaling by enhancing Wnt-induced LRP6 phosphorylation. The LGR5/RSPO complex could promote Wnt signalling via the neutralization of two transmembrane E3 ligases, RNF43 and ZNRF3.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 62.0 kDa. The protein migrates as 66-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifica

Specifica

NP_003658.1
>90% as determined by SDS-PAGE.
Human LGR5, His Tag (LG5-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 22 - Arg 561 (Accession # O75473-1).
-20°C
LGR5
His Tag
Less than 1.0 EU / µg by the LAL method.
Powder
Human
62.0 kDa
100 µg
Gly 22 - Arg 561
LGR5, GPR49, GPR67, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, Leucine-rich repeat-containing G-protein coupled receptor 5
Unconjugated
PBS, pH7.4
HEK293
Other Recombinant Proteins
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