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R&D Systems™ Human PCSK9 (NP_777596) VersaClone cDNA

Codice prodotto. 18761469
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Quantità:
10 μg
Dimensione della confezione:
10µg
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Codice prodotto. Quantità unitSize
18761469 10 μg 10µg
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Codice prodotto. 18761469 Fornitore R&D Systems™ N. del fornitore RDC2709

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

This shuttle vector contains the complete ORF for the gene of interest, along with a Kozak consensus sequence for optimal translation initiation. It is inserted NotI to AscI. The gene insert is flanked with convenient multiple cloning sites which can be used to easily cut and transfer the gene cassette into your desired expression vector.

  • Also known as: FH3; PC9; NARC1; LDLCQ1; NARC-1; HCHOLA3
  • PCSK9 is a member of the subtilisinlike proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway.
  • It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation.
  • It plays a role in cholesterol and fatty acid metabolism.
  • Mutations in PCSK9 have been associated with autosomal dominant familial hypercholesterolemia.
  • Alternatively spliced transcripts encoding different proteins have been described.
  • The insert is sequence verified and the entire plasmid DNA and insert translated sequences are provided.
  • For reasearch use only. Not for use in humans.
TRUSTED_SUSTAINABILITY

Specifica

Gene Proprotein Convertase 9/PCSK9
Numero di accesso NP_777596
Concentrazione 10 μg at 0.2 μg/μL
Formulazione cDNA is provided in 10 mM Tris-Cl, pH 8.5
Tipo di inserto 2092 bp
ID gene (immissione) 255738
Alias gene EC 3.4.21, EC 3.4.21.111, FH3, FH3neural apoptosis regulated convertase 1, FHCL3, HCHOLA3, hypercholesterolemia, autosomal dominant 3, LDLCQ1, NARC1, NARC-1, NARC-1 convertase subtilisin/kexin type 9 preproprotein, NARC1EC 3.4.21.-, Neural apoptosis-regulated convertase 1, PC9, PCSK9, Proprotein convertase 9, proprotein convertase subtilisin/kexin type 9, Subtilisin/kexin-like protease PC9
Content And Storage Store the unopened product at -20°C to -70°C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Specie Human
Quantità 10 μg
Titolo del prodotto
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