missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Recombinant Proteins
  4. Gibco™ Human VISTA Fc Recombinant Protein, PeproTech®

Gibco™ Human VISTA Fc Recombinant Protein, PeproTech®

Codice prodotto. 30019446
Cambia vista
Click to view available options
Quantità:
1 mg
100 μg
250 μg
50 μg
500 μg
Dimensione della confezione:
100µg
1mg
250µg
500µg
50µg
5 product options available for selection
Product selection table with 5 available options. Use arrow keys to navigate and Enter or Space to select.
Codice prodotto. Quantità unitSize
30019446 50 μg 50µg
30019272 500 μg 500µg
30019654 250 μg 250µg
30019268 1 mg 1mg
30019288 100 μg 100µg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 5 options available.
5 options
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Codice prodotto. 30019446 Fornitore Gibco™ N. del fornitore 3104550UG

Please to purchase this item. Need a web account? Register with us today!

Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Recombinant Protein

Recombinant Human VISTA Fc is a 88.2 kDa homodimeric protein of 395 amino acids consisting of the extracellular domain of the mature sequence, as well as a 230-residue C-terminal Fc region linked by two glycines. As a result of glycosylation, the Recombinant Human VISTA Fc migrates to an apparent molecular weight of approximately 60-70 kDa by SDS-PAGE gel, under reducing conditions.

VISTA (V-domain Ig containing suppressor of T-cell activation), also known as B7-H5 or PD-1H, is a product of the VSIR gene. Although VISTA bears sequence homology to PD-L1 it has a different expression pattern. In both mouse and humans, VISTA is expressed predominantly on hematopoietic cells with the highest densities on myeloid cells, and lower levels on T cells. It is usually absent on B cells. VISTA expressed by antigen presenting cells has been shown to directly suppress proliferation and cytokine production of CD4 and CD8 T cells, making it a target for cancer immunotherapy. The reported ligands of VISTA include CD28H, VSIG-3 and VSIG-8.
TRUSTED_SUSTAINABILITY

Specifica

Numero di accesso Q9H7M9
Da utilizzare con (applicazione) Functional Assay
Formato Lyophilized
Formulazione protein with no preservative
ID gene (immissione) 64115
Peso molecolare 44.2 kDa
Nome Human VISTA Fc
Quantità 50 μg
Status giuridico RUO
Concentrazione di endotossine <1 EU/ μg
Alias gene 4632428N05Rik; B7H5; B7-H5; C10orf54; C1H10orf54; C28H10orf54; C4H10orf54; chromosome 10 open reading frame 54; DD1alpha; Death Domain1alpha; Dies1; differentiation of ESCs 1; GI24; PD-1 H; PDCD1 homolog; PD-H1; platelet receptor Gi24; PP2135; RIKEN cDNA 4632428N05 gene; SISP1; sisp-1; Stress-induced secreted protein-1; UNQ730/PRO1412; V-domain Ig suppressor of T cell activation; VISTA; V-set domain-containing immunoregulatory receptor; V-set immunoregulatory receptor; VSIR; V-type immunoglobulin domain-containing suppressor of T-cell activation
Nome comune VISTA
Attività biologica Determined by its ability to bind immobilized human VSIG3 Fc in a functional ELISA
Coniugato Unconjugated
Recombinant Recombinant
Tag proteine Fc-tag
Sequenza FKVATPYSLY VCPEGQNVTL TCRLLGPVDK GHDVTFYKTW YRSSRGEVQT CSERRPIRNL TFQDLHLHHG GHQAANTSHD LAQRHGLESA SDHHGNFSIT MRNLTLLDSG LYCCLVVEIR HHHSEHRVHG AMELQVQTGK DAPSNCVVYP SSSQDSENIT AAGGPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGK
Content And Storage -20°C
Sistema di espressione CHO cells
Forma Lyophilized
Purity or Quality Grade ≥ 95% by SDS-PAGE gel and HPLC analyses.
Vedi altri risultati Mostra meno risultati
Titolo del prodotto
Selezionare un problema

Facendo clic su Invia, l'utente riconosce che potrebbe essere contattato da Fisher Scientific in merito al feedback fornito in questo modulo. Non condivideremo le vostre informazioni per altri scopi. Tutte le informazioni di contatto fornite saranno conservate in conformità con la nostra Politica sulla privacy. Informativa sulla privacy.