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Hydroxychloroquine sulfate, 98%

Codice prodotto. 10646271 Sfoglia Tutto Thermo Scientific Chemicals Prodotti
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Quantità:
25 g
100 g
Imballaggio:
Bottiglia in vetro
Dimensione della confezione:
100g
25g
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10646271 25 g Bottiglia in vetro 25g
10209543 100 g Bottiglia in vetro 100g
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Codice prodotto. 10646271 Fornitore Thermo Scientific Acros N. del fornitore 263010250
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Descrizione

Hydroxychloroquine sulfate, CAS # 747-36-4, is a chemical compound with antiparasitic, antiviral, and anti-rheumatic activities. | CAS: 747-36-4 | C18H26ClN3O·H2SO4 | 433.96 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Hydroxychloroquine sulfate shows antimalarial activity against malaria parasites mainly in the intra-erythrocytic phase of its life cycle. It acts by inhibiting the heme polymerase inside the food vacuole of the parasites
  • It shows an inhibitory activity in autophagy preventing the lysosome fusion with the autophagosome
  • Some studies demonstrated that hydroxychloroquine sulfate, due to its antiviral activity can restrict HIV infection in vitro

Applications

  • Hydroxychloroquine sulfate displays antiviral and anti-rheumatic activities
  • In vitro and in vivo experiments have been performed to investigate the role of hydroxychloroquine sulfate in the treatment of SARS-CoV-2 disease
  • Hydroxychloroquine sulfate can be used in immunofluorescence assays to evaluate the antiviral mechanisms in dengue virus-2 infection. In this disease, this compound can activate the innate immune response
TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 747-36-4
Formula molecolare C18H26ClN3O·H2SO4
Molecular Weight (g/mol) 433.96
Numero MDL MFCD00078203
InChI Key JCBIVZZPXRZKTI-UHFFFAOYSA-N
Sinonimo hydroxychloroquine sulfate, hydroxychloroquine sulphate, ercoquin, plaquinol, toremonil, 2-4-7-chloroquinolin-4-yl amino pentyl ethyl amino ethanol sulfate, hydroxychloroquine sulfate usp, plaquenil tn, hydroxychloroquine; sulfuric acid, dsstox_cid_27788
PubChem CID 12947
IUPAC Name 2-[4-[(7-chloroquinolin-4-yl)amino]pentyl-ethylamino]ethanol;sulfuric acid
SMILES CCN(CCCC(C)NC1=C2C=CC(=CC2=NC=C1)Cl)CCO.OS(=O)(=O)O

Specifica

Materiale o nome chimico Hydroxychloroquine sulfate
Punto di fusione 240.0°C
Colore White
Perdita all'essiccatura 2% max. (105°C, 2 hrs.)
Spettro a infrarossi Authentic
Intervallo percentuale saggio 0.98
Imballaggio Bottiglia in vetro
Quantità 25 g
Indice di Merck 15, 4857
Informazioni di solubilità Solubility in water: soluble. Other solubilities: practically insoluble in alcohol,chloroform,,ether,acetone and acetic acid
Peso formulazione 433.96
Percent Purity 98%
Forma fisica Crystalline Powder
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Safety and Handling

compliance-icons
Product Identifier
  • Hydroxychloroquine sulfate
 Signal Word
  • Attenzione
 Hazard Category
  • Tossicità acuta Categoria 4
  • Corrosione/irritazione della pelle Categoria 2
 Hazard Statement
  • H302-Nocivo se ingerito.
  • H319-Provoca grave irritazione oculare.
 Precautionary Statement
  • P264-Lavare accuratamente dopo l'uso.
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P330+P331-IN CASO DI INGESTIONE: sciacquare la bocca. NON provocare il vomito.
  • P312-Contattare un CENTRO ANTIVELENI/un medico/in caso di malessere.
  • P337+P313-Se l'irritazione degli occhi persiste, consultare un medico.
 Supplemental information
  • MIXTURE LIST-Contain: Hydroxychloroquine sulphate
SDS

RUO – Research Use Only

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