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  7. Hydroxyurea, 98%

Hydroxyurea, 98%

Product Code. 11469782
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Product Code. 11469782 Supplier Thermo Scientific Alfa Aesar Supplier No. A10831.03
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Description

CAS: 127-07-1 | CH4N2O2 | 76.055 g/mol

Hydroxyurea is used as an inhibitor of DNA synthesis and an anti-cancer drug. It is used as a precursor to prepare 1-hydroxy-5,6-dimethyl-1H-pyrimidine-2,4-dione via reaction with 2-methyl-3-oxo-butyric acid ethyl ester. It is used in the treatment of melanoma, resistant chronic myelocytic leukemia and recurrent metastatic or inoperable ovarian. It is also involved in reducing the rate of painful attacks in sickle-cell disease and has anti-retroviral properties in diseases such as AIDS.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Solubility
Soluble in water, hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.

Notes
Moisture sensitive. Store in cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 127-07-1
Formula molecolare CH4N2O2
Molecular Weight (g/mol) 76.055
Numero MDL MFCD00007943
InChI Key VSNHCAURESNICA-UHFFFAOYSA-N
Sinonimo hydroxycarbamide, n-hydroxyurea, hydrea, 1-hydroxyurea, oxyurea, carbamoyl oxime, biosupressin, hydroxycarbamine, onco-carbide, carbamohydroxamic acid
PubChem CID 3657
ChEBI CHEBI:44423
IUPAC Name hydroxyurea
SMILES C(=O)(N)NO

Specifications

Materiale o nome chimico Hydroxyurea
Punto di fusione ∽140°C (decomposition)
Intervallo percentuale saggio 98%
Quantità 1 g
Beilstein 1741548
Informazioni di solubilità Soluble in water,hot alcohol and dimethyl sulfoxide. Insoluble in ethanol and benzene.
Peso formulazione 76.06

Safety and Handling

compliance-icons
Product Identifier
  • Hydroxyurea
 Signal Word
  • Pericolo
 Hazard Category
  • Mutagenicità di cellule germinali Categoria 1B
  • Tossicità per la riproduzione Categoria 1A
 Hazard Statement
  • H340-Può provocare alterazioni genetiche.
  • H360D-Può nuocere al feto.
 Precautionary Statement
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.
 Supplemental information
  • MIXTURE LIST-Contain: Hydroxyurea
SDS

RUO – Research Use Only

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