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Hypoxanthine, 99%
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Descrizione
Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol A (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Hypoxanthine, is used as a marker for energy perturbation in hypoxia/ ischemia. It has been also used in DNA studies to investigate the destabilizing effect it has on DNA duplexes containing hypoxanthine as a base, in a gas phase versus a liquid phase. Hypoxanthine has also been used in studies along with 8-oxoguanine nucleotides to investigate their interaction with human DNA pol å (DNA polymerase alpha) and DNA polymerase I from Bacillus stearothermophilus. It is also used as a pharmaceutical intermediate.
Solubility
It does not mix appreciably with water (1:1400). Small octahedra crystals from water.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents. Stable under recommended storage conditions. Sterilize by filtration through a 0.22 µm filter.
Specifications
Specifications
| Materiale o nome chimico | Hypoxanthine |
| Punto di fusione | >300°C |
| Quantità | 5 g |
| Beilstein | 5811 |
| Indice di Merck | 14,4869 |
| Informazioni di solubilità | It does not mix appreciably with water (1:1400). Small octahedra crystals from water. |
| Peso formulazione | 136.11 |
| Percent Purity | 99% |
Safety and Handling
- Hypoxanthine
- Attenzione
- Tossicità acuta Categoria 4
- Lesione oculare grave/irritazione oculare Categoria 2
- Corrosione/irritazione della pelle Categoria 2
- Tossicità specifica per organi bersaglio (esposizione singola) Categoria 3
- H302-Nocivo se ingerito.
- H315-Provoca irritazione cutanea.
- H319-Provoca grave irritazione oculare.
- H335-Può irritare le vie respiratorie.
- P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
- P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
- P301+P312-IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI/medico/
- P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
- P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
- MIXTURE LIST-Contain: Hypoxanthine
RUO – Research Use Only
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