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Thermo Scientific™ IDEIA™ Lyme Neuroborreliosis Kit
Description
Detect the human IgG and IgM antibodies to Borrelia burgdorferi in the diagnosis of Lyme neuroborreliosis with this enzyme immunoassay.
Detect the intrathecally produced human IgG and IgM antibodies to Borrelia burgdorferi with Thermo Scientific™ IDEIA™ Lyme Neuroborreliosis Kit. The enzyme immunoassay is designed to deliver rapid detection of human intrathecal IgG and IgM antibodies to Borrelia burgdorferi sensu lato as an aid in the diagnosis of Lyme neuroborreliosis.
Lyme borreliosis is a multisystem infection caused by the tickborne spirochete Borrelia burgdorferi sensu lato. Involvement of the nervous system, neuroborreliosis is a common and serious manifestation of Lyme borreliosis. Neuroborreliosis develops in approximately 10% of patients who have not received treatment for the primary stage lesion. A sensitive and reliable diagnostic test for neuroborreliosis is needed as a number of other diseases with similar symptoms exist and, in contrast to these diseases, neuroborreliosis can be treated with antibiotics.
Use IDEIA Lyme Neuroborreliosis Kit for differential diagnosis of Lyme neuroborreliosis from other potential causes of similar symptoms.
- Simple—ready-to-use liquid reagents and concentrates make the assay easy to implement and run
- Excellent sensitivity and specificity—high quality, well characterized antibodies used in the assay provide excellent sensitivity and specificity
- Easy-to-read results
The assay uses purified, native B. afzelii strain DK1 flagellum as test antigen. The flagellum is highly immunogenic, elicits an early, strong and persistent immune response1,2 , and is the major antigen for the intrathecal antibody response3,4. Compared with the conventional antigen, which is based on whole cell extract of the spirochete, the purified, native flagellar antigen improves the diagnostic sensitivity and specificity of serological assays for Lyme neuroborreliosis5,6. Furthermore, the use of flagellum as test antigen is appropriate in all geographical areas as the flagellum shows no significant variation between B. burgdorferi strains.
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Specifications
Specifications
| Content And Storage | 2°C to 8°C |
| Descrizione | IDEIA™ Lyme Neuroborreliosis Enzyme Immunoassay |
| Analiti rilevabili | B. burgdorferi IgG, B. burgdorferi IgM |
| Tipo | Borrelia Testing Kit |
| Include | Microtitration plate, sample diluent, wash buffer, IgG positive control, IgM negative control, flagellum conjugate, reconstitution buffer, peroxidase complex, substrate TMB, stop solution, instruction booklet |
| Quantità | 48 Tests |
Safety and Handling
- Pericolo
- Tossicità per la riproduzione Categoria 1B
- H360D-Può nuocere al feto.
- P201-Procurarsi istruzioni specifiche prima dell'uso.
- P202-Non manipolare prima di avere letto e compreso tutte le avvertenze.
- P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
- P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.
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