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IFITM3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11714-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16898973

  • 121.38€ / 20µL

Spedizione stimata: 05-10-2022
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Descrizione

Descrizione

11714-1-AP is a rabbit polyclonal antibody raised against the full-length of human IFITM3.

IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-alpha and IFN-gamma. IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.
Specifica

Specifica

IFITM3
Polyclonal
Unconjugated
IFITM3
1 8U, Fragilis, IFITM3, IP15
Rabbit
Antigen Affinity Chromatography
RUO
10410, 361673, 66141
-20°C
Liquid
Immunofluorescence, Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Paraffin)
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P26376, Q01628, Q9CQW9
Ifitm3
IFITM3 Fusion Protein Ag2285
20 μL
Primary
Human, Rat, Mouse
Antibody
IgG
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Documenti
Certificati
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Offerte speciali