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IL-4 Mouse, anti-Human, R718, Clone: MP4-25D2, BD Horizon™
Mouse Monoclonal Antibody
372.00€ - 555.00€
Specifica
| Antigene | IL-4 |
|---|---|
| Clone | MP4-25D2 |
| Applicazioni | Flow Cytometry |
| Classificazione | Monoclonal |
| Coniugato | R718 |
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
|---|---|---|---|---|---|---|---|---|---|
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
|
17207774
|
BD Biosciences
566981 |
25 Tests |
372.00€
25 tests |
Spedizione stimata: 22-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
|
17297764
|
BD Biosciences
566980 |
100 Tests |
555.00€
100 tests |
Spedizione stimata: 22-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
Descrizione
The MP4-25D2 monoclonal antibody specifically binds to Interleukin-4 (IL-4). IL-4 is also known as Lymphocyte stimulatory factor 1, B cell stimulatory factor 1 (BSF-1), or B cell growth factor 1 (BCGF-1). IL-4 is produced by activated T cells, basophils, and mast cells. IL-4 is a multifunctional cytokine and growth factor that affects a variety of different target cell types. IL-4 can costimulate T cell proliferation and survival, as well as help drive Th2-like cell differentiation and effector functions. It costimulates B cell proliferation and survival, and can help B cells differentiate into IgG4- or IgE-producing cells. IL-4 can also diminish the proinflammatory functions of monocytes and macrophages. IL-4 exerts its biological effects by binding with high affinity to cell surface CD124 (IL-4Rα chain). CD124 forms signaling IL-4 receptor complexes with either CD132/common γ chain or CD213a1/IL-13Rα1 to form either Type I or Type II IL-4 Receptor complexes, respectively. The immunogen used to generate the MP4-25D2 hybridoma was purified recombinant human IL-4. This is a neutralizing antibody. The MP4-25D2 antibody has been reported to crossreact with IL-4 from rhesus monkeys. The use of the MP4-25D2 antibody for epitope mapping of human IL-4 has been described.
Specifica
| IL-4 | |
| Flow Cytometry | |
| R718 | |
| Mouse | |
| Human | |
| Refrigerate Upon Arrival |
| MP4-25D2 | |
| Monoclonal | |
| Liquid | |
| RUO | |
| Primary |