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Invitrogen™ IL4R Polyclonal Antibody
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Codice prodotto. 15517792
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità unitSize
15517792 100 μg 100µg
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Codice prodotto. 15517792 Fornitore Invitrogen™ N. del fornitore PA547297

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

Goat Polyclonal Antibody

In direct ELISAs and Western blots, less than 5% cross-reactivity with recombinant human (rh) IL-1 sRI, rhIL-1 sRII, rhIL-2 sR alpha, rhIL-2 sR beta, rhIL-2 sR gamma, rhIL-3 sR alpha, and rhIL-5 sR alpha is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
TRUSTED_SUSTAINABILITY

Specifica

Antigene IL4R
Applicazioni Flow Cytometry, Western Blot
Classificazione Polyclonal
Concentrazione 0.2 mg/mL
Coniugato Unconjugated
Formulazione PBS with 5% trehalose and No Preservative
Gene IL4R
N. accesso geni P24394
Alias gene 582J2.1; CD124; il-4 receptor; IL-4 receptor alpha chain; IL-4 receptor subunit alpha; IL-4-binding protein; IL4-BP; Il4r; IL4R nirs variant 1; IL-4R subunit alpha; IL4RA; IL-4RA; IL-4R-alpha; interleukin 4 receptor; interleukin 4 receptor, alpha; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha; Soluble IL-4 receptor subunit alpha; Soluble interleukin-4 receptor subunit alpha
Simboli geni IL4R
Specie ospite Goat
Immunogeno Sf 21-derived recombinant human IL-4 R alpha.
Metodo di purificazione Antigen affinity chromatography
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 3566
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Forma Lyophilized
Isotype IgG
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