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Indomethacin, 98%
Beschreibung
It is a non-steroidal anti-inflammatory drug, it is used in the treatment of musculoskeletal and joint disorders including osteoarthritis, rheumatoid arthritis, gout, bursitis and tendinitis. It finds its application as gout suppressant, non-steroidal anti-inflammatory drug and analgesic. It also plays many biological roles. Additionally, Indomethacin displays adipogenic actions via binding and activation of PPARγ (peroxisome proliferator-activated receptor γ), a ligand-activated transcription factor known to play an important role in adipogenesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Soluble in acetone (40 mg/mL - clear, yellow solution), ethanol (20 mg/mL), ether, castor oil; Soluble in chloroform (50 mg/mL - clear, yellow, extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water.
Notes
Store away from oxidizing agents, strong bases and light. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
Spezifikation
Spezifikation
| Materiale o nome chimico | Indomethacin |
| Punto di fusione | 158°C to 161°C |
| Intervallo percentuale saggio | 0.98 |
| Quantità | 5 g |
| Numero UN | UN2811 |
| Beilstein | 497341 |
| Sensibilità | Light sensitive |
| Indice di Merck | 14,4968 |
| Informazioni di solubilità | Soluble in acetone (40mg/mL- clear,yellow solution),ethanol (20mg/mL),ether,castor oil; Soluble in chloroform (50mg/mL- clear,yellow,extremely viscous solution); decomposed by strong alkali but stable in neutral or slightly acidic media; insoluble in water. |
| Peso formulazione | 357.8 |
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Sicherheit und Handhabung
- Indomethacin
- Pericolo
- Tossicità acuta Categoria 1
- Tossicità per la riproduzione Categoria 1B
- Sensibilizzazione della pelle Categoria 1
- H300-Letale se ingerito.
- H317-Può provocare una reazione allergica cutanea.
- H360FD-Può nuocere alla fertilità. Può nuocere al feto.
- P201-Procurarsi istruzioni specifiche prima dell'uso.
- P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
- P301+P310-IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI/un medico
- P302+P352-IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/.
- P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.
- P330-Sciacquare la bocca.
- MIXTURE LIST-Contain: Indomethacin
RUO – Research Use Only
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