missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Chemicals
  4. Organic compounds
  5. Organoheterocyclic compounds
  6. Indoles and derivatives
  7. Indomethacin, 99+%
  • missing translation for 'structureSearchLink'
  • Print

Indomethacin, 99+%

Product Code. 15425529
missing translation for 'orderingAttributeHoverText'
Quantità:
1 g
5 g
25 g
missing translation for 'unitSize'
1g
25g
5g
This item is not returnable. View return policy

Product Code. 15425529

missing translation for 'mfr': Thermo Scientific Alfa Aesar J63255.03

Richiesta di formato massivo o personalizzato

Effettua il per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso!

This item is not returnable. View return policy

Description

Indomethacin, CAS # 53-86-1, is an indole-based nonsteroidal anti-inflammatory (NSAID). | CAS: 53-86-1 | C19H16ClNO4 | 357.79 g/mol

Non-selective cyclooxygenase inhibitorIndomethacin acts as an antiinflammatory, antipyretic and analgesic. It serves as an inhibitor cyclooxygenase such as Cox-1 and Cox-2. In addition to this, it is used as a prescription medication in order to reduce fever, stiffness, swelling and pain.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • Indomethacin is a synthetic NSAID of the indole family that inhibits cyclooxygenase and reduces prostaglandin and pyrogen release
  • Indomethacin may suppress the multi-drug resistant transporter and thereby increase the efficacy of antineoplastics
  • Indomethacin activates phosphatases that inhibit signaling pathways associated with cancer cell migration and proliferation

Applications

  • Indomethacin may be used for the laboratory study of cancer cell proliferation, tumorigenesis and drug interactions
  • Indomethacin may be used for laboratory study of the effect of inhibiting the multi-drug resistance transporter, or for downregulation of survival signaling in cells via survivin
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 53-86-1
Formula molecolare C19H16ClNO4
Molecular Weight (g/mol) 357.79
Numero MDL MFCD00057095
InChI Key CGIGDMFJXJATDK-UHFFFAOYSA-N
Sinonimo indomethacin, indometacin, indocin, indometacine, indomethacine, indocid, metindol, amuno, indomethazine, imbrilon
PubChem CID 3715
ChEBI CHEBI:49662
IUPAC Name 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid
SMILES CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O

Specifications

Materiale o nome chimico Indomethacin
Punto di fusione 158°C to 161°C
Colore White
Quantità 1 g
Numero UN UN2811
Beilstein 497341
Sensibilità Light sensitive
Indice di Merck 14,4968
Informazioni di solubilità Soluble in ethanol and dimethyl sulfoxide.
Peso formulazione 357.8
Percent Purity ≥99%
Forma fisica Powder
Show More Show Less

RUO – Research Use Only

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.