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ING4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
140.00€ - 399.00€
Specifica
Antigene | ING4 |
---|---|
Concentrazione | 0.13 mg/mL |
Applicazioni | Immunoprecipitation, Western Blot |
Classificazione | Polyclonal |
Coniugato | Unconjugated |
Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
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Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
16897103
|
Proteintech
10617-1-AP-20UL |
20 μL |
140.00€
20µL |
Spedizione stimata: 14-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
16887103
|
Proteintech
10617-1-AP-150UL |
150 μL |
399.00€
150µL |
Spedizione stimata: 14-05-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
Descrizione
This antibody is a rabbit polyclonal antibody raised against full length human ING4 antigen.
The ING4 gene belongs to the ING (Inhibitor of Growth) family of tumor suppressors. All five members of the ING protein family identified to date contain a highly conserved plant homeodomain (PHD) finger motif at the C-terminal end, which is found in transcription factors that modulate chromatin structure. ING proteins have been shown to form transcriptional complexes leading to activation of responsive genes that mediate a wide range of cellular functions, including growth arrest, DNA repair, gene transcription, apoptosis, and senescence. The candidate tumor suppressor ING4 has a role in brain tumor pathogenesis, and is involved in regulating tumor growth and angiogenesis. Expression of ING4 is reduced in gliomas compared to normal brain tissue, and ING4 reduction correlates with progression from lower to higher grades of tumors. ING4 physically interacts with the p65 (RelA) subunit of NF-kB and represses transcription of NF-kB responsive genes. Inactivating mutations in ING4 transcripts have been described in various human cancer cell lines, and deletion of the ING4 locus has been detected in 10-20% of human breast cancer cell lines and tumors.Specifica
ING4 | |
Immunoprecipitation, Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q8C0D7, Q9UNL4 | |
28019, 297597, 51147 | |
ING4 Fusion Protein Ag0960 | |
Primary | |
-20°C | |
ING4 |
0.13 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
ING4, Inhibitor of growth protein 4, my036, p29ING4 | |
Ing4 | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |