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Kanamycin monosulfate, Cell Culture Grade

Codice prodotto. 15463399
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Quantità:
5 g
Dimensione della confezione:
5g
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Codice prodotto. 15463399

Marca: Thermo Scientific Alfa Aesar J60668.06

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Descrizione

Kanamycin monosulfate, CAS # 25389-94-0, is an aminoglycoside sulfate salt with antibacterial activity. | CAS: 25389-94-0 | C18H38N4O15S | 582.575 g/mol

Kanamycin monosulfate, is used as an aminoglycoside antibiotic. Kanamycin can be used as a selection agent in several types of isolation media.Kanamycin sulfate from Streptomyces kanamyceticus has been used in tissue culture media. Kanamycin sulfate can also be used as a selection agent for cells transformed with kanamycin B resistance gene. It is recommended for use in cell culture applications at 100mg/mL.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Kanamycin monosulfate is the sulfate salt form of kanamycin A

• It was isolated from Streptomyces kanamyceticus

• This compound inhibits translocation during protein biosynthesis. It binds to the 30S ribosomal subunit, causing misreading of the mRNA sequence

Application

• Kanamycin monosulfate shows antibacterial activity. It is effective against gram-positive and gram-negative bacteria, as well as Mycoplasma species

• This compound is also involved in translating prokaryotic ribosomes

• In molecular biology experiments, it is commonly used to select and isolate transformants expressing the kanamycin resistance gene, and plants that have the NPT II (APH3) gene incorporated

Literature References

Patel, K. N.; Limgavkar, R. S.; Raval, H. G.; Patel, K. G.; Gandhi, T. R. High-Performance Liquid Chromatographic Determination of Cefalexin Monohydrate and Kanamycin Monosulfate with Precolumn Derivatization. J. Liq. Chromatogr. Related Technol. 2015, 38 (6), 716-721.

Chi, Z.; Rong, Y. J.; Li, Y.; Tang, M. J.; Chi, Z. M. Biosurfactins production by Bacillus amyloliquefaciens R3 and their antibacterial activity against multi-drug resistant pathogenic E. coli. Bioprocess. Biosyst. Eng. 2015, 38 (5), 853-861.

TRUSTED_SUSTAINABILITY

Identificatori chimici

CAS 25389-94-0
Formula molecolare C18H38N4O15S
Molecular Weight (g/mol) 582.575
Numero MDL MFCD00070253
InChI Key OOYGSFOGFJDDHP-IZQIRFRQSA-N
Sinonimo Kanamycin A
PubChem CID 134129479
IUPAC Name (2R,3S,4S,5S,6R)-2-(aminomethyl)-6-[(1R,2S,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5R,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxyoxane-3,4,5-triol;sulfuric acid
SMILES C1C(C(C(C(C1N)OC2C(C(C(C(O2)CN)O)O)O)O)OC3C(C(C(C(O3)CO)O)N)O)N.OS(=O)(=O)O

Specifica

Materiale o nome chimico Kanamycin monosulfate
Tipo Kanamycin Monosulfate
Forma fisica Powder
Colore White
Quantità 5 g
Indice di Merck 14,5281
Informazioni di solubilità Soluble in water at 10mg/ml
Peso formulazione 582.58
Grado Cell Culture

Safety and Handling

compliance-icons
Product Identifier
  • Kanamycin monosulfate, Cell Culture Grade
 Signal Word
  • Pericolo
 Hazard Category
  • Tossicità per la riproduzione Categoria 1B
  • Sensibilizzante delle vie respiratorie Categoria 1
  • Sensibilizzazione della pelle Categoria 1
 Hazard Statement
  • H317-Può provocare una reazione allergica cutanea.
  • H334-Può provocare sintomi allergici o asmatici o difficoltà respiratorie se inalato.
  • H360FD-Può nuocere alla fertilità. Può nuocere al feto.
 Precautionary Statement
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P261-Evitare di respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
  • P304+P340-IN CASO DI INALAZIONE: trasportare l'infortunato all'aria aperta e mantenerlo a riposo in posizione che favorisca la respirazione.
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.
  • P342+P311-In caso di sintomi respiratori: contattare un CENTRO ANTIVELENI/un medico/ .
 Supplemental information
  • MIXTURE LIST-Contiene: Kanamycin sulphate
SDS

RUO – Research Use Only

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