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KCNQ3 Rabbit anti-Human, Porcine, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 19966-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899444

  • 121.38€ / 20µL

Spedizione stimata: 10-10-2022
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Descrizione

Descrizione

The antibody recognizes the C-term of KCNQ3.

KCNQs are members of the voltage-dependent non-inactivating potassium channel family. Currently there are five known KCNQs (KCNQ1-5) found in the central nervous system and KCNQ2 and 3 have demonstrated their importance in M-current activation. Studies have shown that KCNQ2 and KCNQ3 form heteromultimers that, when formed, substantially increase the M-current. Inhibition of M-current controls neuron excitability throughout the nervous system as well as the responsiveness to synaptic inputs. Genetic mutations in these proteins have been linked to disorders such as benign familial neonatal convulsions (BFNC), deafness, neuropathic pain and epilepsy.
Specifica

Specifica

KCNQ3
Polyclonal
Unconjugated
KCNQ3
BFNC2, EBN2, KCNQ3, KQT like 3, KV7.3
Rabbit
Antigen Affinity Chromatography
RUO
100157152, 3786
-20°C
Liquid
Western Blot
0.13 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
O43525
KCNQ3
Peptide
20 μL
Primary
Porcine, Human
Antibody
IgG
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