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  8. L(+)-Amethopterin hydrate, 99%, Thermo Scientific Chemicals

L(+)-Amethopterin hydrate, 99%, Thermo Scientific Chemicals

Catalog Number 10002690
Click to view available options
Quantità:
25 mg
100 mg
500 mg
Imballaggio:
Glass Bottle
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
133073-73-1
C20H22N8O5
454.45
MFCD00150847
FBOZXECLQNJBKD-UGPWUYPHNA-N
l +-amethopterin dihydrate, methotrexate dihydrate, dihydrate methotrexate, 2s-2-4-2,4-diaminopteridin-6-yl methyl methylamino phenyl carbonylamino pentanedioic acid, hydrate, hydrate
45157423
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid;dihydrate
CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
133073-73-1
C20H22N8O5
454.45
MFCD00150847
FBOZXECLQNJBKD-UGPWUYPHNA-N
l +-amethopterin dihydrate, methotrexate dihydrate, dihydrate methotrexate, 2s-2-4-2,4-diaminopteridin-6-yl methyl methylamino phenyl carbonylamino pentanedioic acid, hydrate, hydrate
45157423
(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid;dihydrate
CN(CC1=CN=C2N=C(N)N=C(N)C2=N1)C1=CC=C(C=C1)C(=O)N[C@@H](CCC(O)=O)C(O)=O

Descrizione

L(+)-Amethopterin hydrate, CAS # 133073-73-1, is an effective inhibitor of dihydrofolate reductase, which may have anti-tumor activity.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description
• L(+)-Amethopterin hydrate, is a potent inhibitor of dihydrofolate reductase
• It has tumoricidal activity
Applications
• L(+)-Amethopterin hydrate is an inhibitor of dihydrofolate reductase
• It can be used in anti-tumor studies
• It is a cell cycle arrest agent, which can inhibit synthesis of DNA, RNA, and proteins
• It can also inhibit production of pro-inflammatory cytokines
TRUSTED_SUSTAINABILITY
Materiale o nome chimico L(+)-Amethopterin hydrate
Punto di fusione 195°C
Colore Yellow to Orange
Spettro a infrarossi Authentic
Intervallo percentuale saggio 98.5% min. (HPLC)
Imballaggio Glass Bottle
Quantità 25 mg
Indice di Merck 14, 5985
Rotazione specifica + 21.5
Informazioni di solubilità Solubility in water: insoluble in water. Other solubilities: insoluble in alcohol,chloroform,ether,slightly soluble in dilute hydrochloric acid,soluble in dilute solutions of alkali hydroxides a
Peso formulazione 454.44
Percent Purity 99%
Forma fisica Crystalline Powder
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Sicurezza e movimentazione

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Identificativo prodotto
  • L(+)-Amethopterin hydrate
 Avvertenza
  • Pericolo
 Categoria di pericolo
  • Tossicità acuta Categoria 3
  • Mutagenicità di cellule germinali Categoria 1B
  • Tossicità per la riproduzione Categoria 1A
 Indicazioni di pericolo
  • H360D-Può nuocere al feto.
  • H340-Può provocare alterazioni genetiche.
  • H301-Tossico se ingerito.
 Consigli di prudenza
  • P201-Procurarsi istruzioni specifiche prima dell'uso.
  • P301+P310-IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI/un medico/
  • P308+P313-IN CASO di esposizione o di possibile esposizione, consultare un medico.

RUO – Research Use Only

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