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LGI1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA520491
346.50 EUR valido fino al 2025-02-13
Usa il codice promo "24070" per avere il tuo prezzo promozionale.
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Descrizione
A suggested positive control is Hela cell lysate. PA5-20491 can be used with blocking peptide PEP-0611.
The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist.
Specifica
LGI1 | |
Polyclonal | |
Unconjugated | |
LGI1 | |
ADLTE; ADPAEF; ADPEAF; BB130740; EPITEMPIN; Epitempin 1; Epitempin-1; EPT; ETL1; IB1099; leucine rich glioma inactivated 1; leucine-rich glioma inactivated 1; leucine-rich glioma-inactivated protein 1; leucine-rich repeat LGI family, member 1; leucine-rich, glioma inactivated 1; LGI1; OTTHUMP00000020121; OTTHUMP00000020122; UNQ775/PRO1569 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
252892, 56839, 9211 | |
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
Liquid |
Immunohistochemistry, Western Blot | |
1 mg/mL | |
PBS with 0.02% sodium azide | |
O95970, Q8K4Y5, Q9JIA1 | |
LGI1 | |
A 14 amino acid peptide from near the center of human LGI1. | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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