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Invitrogen™ MD-1 Polyclonal Antibody
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Codice prodotto. 12858452
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità unitSize
12858452 100 μg 100µg
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Codice prodotto. 12858452 Fornitore Invitrogen™ N. del fornitore PA520261

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Descrizione

Rabbit Polyclonal Antibody

A suggested positive control is Daudi cell lysate. PA5-20261 can be used with blocking peptide PEP-0376.

MD-1, also known as LY86, is a glycoprotein involved in innate immunity. It is a component of the RP105/MD-1 complex, which is expressed primarily in immune cells like B-cells. MD-1 is structurally similar to MD-2, sharing only 16% sequence identity, yet both are implicated in lipopolysaccharide recognition. The protein contains the ML (MD-2-related lipid-recognition) domain, which is conserved across various species and mediates diverse biological functions by interacting with specific lipids. Structurally, MD-1 is characterized by a beta-rich fold consisting of multiple strands, which is integral to its biological activities. Though MD-1 mainly associates with RP105, its role in lipid recognition suggests functional similarities with proteins such as GM2A and NPC2, implying participation in broader immune signaling pathways.
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Specifica

Antigene MD-1
Applicazioni Immunohistochemistry, Western Blot
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 0.02% sodium azide
Gene LY86
N. accesso geni O88188, O95711
Alias gene dJ80N2.1; Ly86; Ly-86; Lymphocyte antigen 86; MD1; MD-1; MD-1, RP105-associated; MMD-1; Protein MD-1; RP1-80N2.1
Simboli geni LY86
Specie ospite Rabbit
Immunogeno A 15 amino acid peptide from near the center of human MD-1.
Metodo di purificazione Antigen affinity chromatography
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 17084, 291359, 9450
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Forma Liquid
Isotype IgG
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