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Tocris Bioscience™ Me VH 032, amine

Codice prodotto. 18707376
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Quantità:
100 mg
Dimensione della confezione:
100mg
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18707376 100 mg 100mg
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Codice prodotto. 18707376 Fornitore Tocris Bioscience™ N. del fornitore FAB9610U100UG
 Articolo soggetto a restrizioni
Spedizione stimata: 03-08-2026
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Descrizione

Amine functionalized VHL ligand for PROTAC™ research

Me VH 032, amine is a derivative of the von Hippel-Lindau (VHL) ligand, VH 032 for use as a precursor to a PROTAC® that hijacks VHL as the E3 ubiquitin ligase component. Me VH 032, amine is supplied with a primary amine functional handle, for ready conjugation to a linker/target protein ligand. Introduction of the methyl group at the benzylic position of VH 032 is associated with improved binding affinity.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Require a different derivative? Get in touch

TRUSTED_SUSTAINABILITY

Specifications

Materiale o nome chimico (4R)-3-Methyl-L-valyl-4-hydroxy-N-[(1S)-1-[4-(4-methyl-5-thiazolyl)phenyl]ethyl]-L-prolinamide dihydrochloride
CAS 2504950-56-3
Quantità 100 mg
Bersaglio Degrader Building Blocks
Formula molecolare C23H32N4O3S.2HCl
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