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MIB1 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Marca:  Proteintech 11893-1-AP-20UL

Dettagli aggiuntivi : Peso : 0.00010kg

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Codice prodotto. 16899263

  • 121.38€ / 20µL

Spedizione stimata: 29-09-2022
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Descrizione

Descrizione

MIB is an E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. This protein positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors. MIB probably mediates ubiquitination and subsequent proteasomal degradation of DAPK1, thereby antagonizing anti-apoptotic effects of DAPK1 to promote TNF-induced apoptosis.
Specifica

Specifica

MIB1
Polyclonal
Unconjugated
MIB1
DAPK interacting protein 1, DIP 1, DIP1, KIAA1323, MIB, MIB1, Mind bomb homolog 1, ZZANK2, ZZZ6
Rabbit
Antigen Affinity Chromatography
RUO
57534
-20°C
Liquid
Western Blot, Immunohistochemistry (Paraffin), Immunoprecipitation
0.23 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q86YT6
MIB1
MIB1 Fusion Protein Ag2507
20 μL
Primary
Human
Antibody
IgG
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