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Thermo Scientific Chemicals Mitomycin C, contains 2 mg Mitomycin C and 48 mg NaCl

Product Code. 10286710 Shop All Thermo Scientific Chemicals Products
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Product Code. 10286710 Supplier Thermo Scientific Chemicals Supplier No. 226940020
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Description

Mitomycin C, CAS # 50-07-7, is a methylazirinopyrroloindoledione complex isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. It is a versatile and potent compound with antibiotic activity and may have potential therapeutic value in the treatment of cancer. | CAS: 50-07-7 | C15H18N4O5 | 334.32 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General description

  • Mitomycin C is a water soluble, blue-violet crystalline powder, unstable in light and acidic conditions, but may be stably stored at 2-8°c
  • Bio-reduced mitomycin C generates oxygen radicals, alkylates DNA, and produces inter-strand DNA cross-links, thereby inhibiting DNA synthesis

Applications

  • Mitomycin C is preferentially toxic to hypoxic cells that are resistant to cancer therapy, and is therefore used to study its potential therapeutic effect on advanced stages of cancer
  • At high concentrations, mitomycin C inhibits RNA and protein synthesis and demonstrates strong antibiotic properties towards both Gram-positive and Gram-negative bacteria
TRUSTED_SUSTAINABILITY

Specifications

Materiale o nome chimico Mitomycin C
CAS 50-07-7, 7647-14-5
Punto di fusione >360.0°C
Colore Blue-Violet
Imballaggio Ampoule
Formula molecolare C15H18N4O5
Numero MDL MFCD00078109
Quantità 2 mg
Indice di Merck 15, 6300
Sinonimo mitomycin c, mitomycin, ametycine, mutamycin, ametycin, mitocin-c, mitomycinum, mytomycin, mytozytrex, mitomycin-c
Informazioni di solubilità Solubility in water: soluble. Other solubilities: soluble in methanol, acetone, butyl acetate and, cyclohexanone;, slightly soluble in benzene, ccl4, diethyl ether;, practically insoluble in petroleum ether.
InChI Key NWIBSHFKIJFRCO-WUDYKRTCSA-N
SMILES CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
Molecular Weight (g/mol) 334.32
PubChem CID 5746
ChEBI CHEBI:27504
Peso formulazione 334.32
Percent Purity ≥99% with regard to the non-formulated material
Forma fisica Powder
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Safety and Handling

compliance-icons compliance-icons
Product Identifier
  • Mitomycin C
 Signal Word
  • Attenzione
 Hazard Category
  • Tossicità acuta Categoria 4
  • cancerogenicità Categoria 2
 Hazard Statement
  • H351-Sospettato di provocare il cancro.
  • H302-Nocivo se ingerito.
 Precautionary Statement
  • P280-Indossare guanti/indumenti protettivi/Proteggere gli occhi/il viso.
  • P301+P312-IN CASO DI INGESTIONE accompagnata da malessere: contattare un CENTRO ANTIVELENI/medico/
SDS

RUO – Research Use Only

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