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ACROBiosystems Mouse Fc gamma RIIB / CD32b Protein, His Tag (SPR & BLI verified)
287.41€ - 2612.85€
Specifica
| Numero di accesso | NP_001070657.1 |
|---|---|
| Peso molecolare | 22.2 kDa |
| Sorgente | Mouse CD32b, His Tag (SPR and BLI verified) (CDB-M52H7) is expressed from human 293 cells (HEK293). It contains AA Thr 40 - Arg 217 (Accession # NP_001070657.1). |
| Immunogeno | Thr 40 - Arg 217 |
| Requisiti di stoccaggio | -20°C |
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
|---|---|---|---|---|---|---|---|---|---|
| Codice del prodotto | Marca | Quantità | Prezzo | Quantità e disponibilità | |||||
|
16457359
|
ACROBiosystems
CDB-M52H7-100UG |
100 μg |
365.80€
100µg |
Spedizione stimata: 26-04-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
|
17106211
|
ACROBiosystems
CDB-M52H7-50UG |
50 μg |
287.41€
50µg |
Spedizione stimata: 26-04-2024 Eseguire il login per visualizzare lo stock disponibile |
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|
16467359
|
ACROBiosystems
CDB-M52H7-1MG |
1 mg |
2612.85€
1mg |
Spedizione stimata: 26-04-2024 Eseguire il login per visualizzare lo stock disponibile |
Effettua il login per acquistare questo articolo Hai bisogno di un conto web ? Registrati oggi stesso! | ||||
Descrizione
Receptors for the Fc region of IgG (Fc γ R) are members of the Ig superfamily that function in the activation or inhibition of immune responses. Three classes of human Fc γ Rs: RI (CD64), RII (CD32), and RIII (CD16), which generate multiple isoforms, are recognized. There are three genes for human Fcγ RII /CD32 (A, B, and C) and one for mouse Fcγ RII B (CD32B). CD32 is a low affinity receptor for IgG. Low affinity immunoglobulin gamma Fc region receptor II-b (FCGR2B) is also known as CD32b, FCG2, IGFR2. CD32B is expressed on B cells and myeloid dendritic cells. Ligation of CD32B on B cells downregulates antibody production and may, in some circumstances, promote apoptosis. Co-ligation of CD32B on dendritic cells inhibits maturation and blocks cell activation. CD32B may also be a target for monoclonal antibody therapy for malignancies.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.2 kDa. The protein migrates as 32-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Specifica
| NP_001070657.1 | |
| Mouse CD32b, His Tag (SPR and BLI verified) (CDB-M52H7) is expressed from human 293 cells (HEK293). It contains AA Thr 40 - Arg 217 (Accession # NP_001070657.1). | |
| -20°C | |
| Fc gamma RIIB / CD32b | |
| Mouse | |
| PBS, pH7.4 | |
| HEK293 | |
| MABSol™ Fc Receptors |
| 22.2 kDa | |
| Thr 40 - Arg 217 | |
| FCGR2B,CD32b,CD32,FCG2,IGFR2,CDw32 | |
| Unconjugated | |
| His Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |