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Invitrogen™ Myc Tag Polyclonal Antibody
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Codice prodotto. 11578711
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Quantità:
100 μL
Dimensione della confezione:
100µL
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Codice prodotto. Quantità unitSize
11578711 100 μL 100µL
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Codice prodotto. 11578711 Fornitore Invitrogen™ N. del fornitore PA1981

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Descrizione

Rabbit Polyclonal Antibody

PA1-981 detects c-Myc tagged proteins. PA1-981 has been successfully used in WB and immunofluorescence procedures to detect the presence of expressed c-Myc tagged proteins in transfected mammalian cells. PA1-981 immunogen is a synthetic peptide corresponding to residues C E(410) Q K L I S E E D L(419) of human c-Myc. PA1-981 immunizing peptide (PEP-035) is available for use in neutralization and control experiments.

Myc is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Myc Tag
Applicazioni ChIP Assay, Immunoprecipitation, Western Blot, Immunocytochemistry
Classificazione Polyclonal
Concentrazione 1 mg/mL
Coniugato Unconjugated
Formulazione PBS with 1mg/mL BSA and 0.05% sodium azide
Gene MYC
N. accesso geni P01106
Alias gene 46-0603; AU016757; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; Niard; Nird; Proto-oncogene c-Myc; R95025; R950-25; transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Simboli geni MYC
Specie ospite Rabbit
Immunogeno Synthetic peptide corresponding to residues C E(410) Q K L I S E E D L(419) of human c-Myc.
Metodo di purificazione Antigen affinity chromatography
Quantità 100 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 4609
Target Species Tag
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Forma Liquid
Isotype IgG
Target Molecule Tag
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