Learn More
N-Ethylmaleimide, 98+%
Description
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Cysteine alkylating agent N-Ethylmaleimide is a protein thiol modifier which inhibits apoptotic DNA fragmentation. It is a sulfhydryl reagent and finds application in experimental biochemical studies as well as in enzymology. It is involved in the modification of cysteine residues in proteins and peptides. It acts as a Michael acceptor and reacts with nucelophiles like thiols. It is employed in the inhibition of Mg2+-dependent internucleosomal DNA fragmentation.
Solubility
Soluble in ethanol, water, chloroform, methanol and toluene.
Notes
Light sensitive. Store in cool place. Incompatible with strong oxidizing agents, strong acids and strong bases.
Specifications
Specifications
| Materiale o nome chimico | N-Ethylmaleimide |
| Punto di fusione | 43°C to 46°C |
| Punti di ebollizione | 209°C to 211°C |
| Punto d'infiammabilità | 73°C (163°F) |
| Odore | Pungent |
| Quantità | 10 g |
| Numero UN | UN2928 |
| Beilstein | 112448 |
| Sensibilità | Light sensitive |
| Indice di Merck | 14,3822 |
| Show More |
Safety and Handling
- N-Ethylmaleimide
- Pericolo
- Tossicità acuta Categoria 2
- Corrosione/irritazione della pelle Categoria 1B
- Tossicità acuta Categoria 4
- Sensibilizzazione della pelle Categoria 1
- H300-Letale se ingerito.
- H312-Nocivo per contatto con la pelle.
- H314-Provoca gravi ustioni cutanee e gravi lesioni oculari.
- H317-Può provocare una reazione allergica cutanea.
- P260-Non respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
- P301+P310-IN CASO DI INGESTIONE: contattare immediatamente un CENTRO ANTIVELENI/un medico
- P303+P361+P353-IN CASO DI CONTATTO CON LA PELLE (o con i capelli): togliere immediatamente tutti gli indumenti contaminati. Sciacquare la pelle/fare una doccia.
- P305+P351+P338-IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
- P405-Conservare sotto chiave.
- P501b-Smaltire il prodotto/recipiente in conformità con le disposizioni locali/regionali/nazionali/internazionali.
RUO – Research Use Only
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.