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Invitrogen™ p53R2 Polyclonal Antibody
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Codice prodotto. 15925505
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Quantità:
100 μg
Dimensione della confezione:
100µg
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Codice prodotto. Quantità unitSize
15925505 100 μg 100µg
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Codice prodotto. 15925505 Fornitore Invitrogen™ N. del fornitore PA579938

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Descrizione

Rabbit Polyclonal Antibody

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Thymus Tissue, MCF-7 Cell, A431 Cell, HELA Cell.

The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. Several novel molecules involved in p53 signaling, including p53R2, Chk2, p53AIP1, Noxa, PIDD, and PID/MTA2, were recently discovered. p53R2 is a p53 inducible gene that contains a p53 binding sequence and encodes a subunit of the enzyme ribonucleotide reductase. p53R2 is induced by the reagents, ultraviolet and -gamma-irradiation that cause DNA damages. The product of p53R2 gene is directly involved in the p53 checkpoint for repair of damaged DNA. The isoform of the p53 family member p73 also induces p53R2 expression. p53R2 is an important target of p53 for tumor suppression.
TRUSTED_SUSTAINABILITY

Specifica

Antigene p53R2
Applicazioni Western Blot
Classificazione Polyclonal
Concentrazione 500 μg/mL
Coniugato Unconjugated
Formulazione PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
Gene Rrm2b
N. accesso geni Q6PEE3, Q7LG56
Alias gene MTDPS8A; MTDPS8B; p53-inducible ribonucleotide reductase small subunit 2 homolog; p53-inducible ribonucleotide reductase small subunit 2 short form beta; p53-inducible ribonucleotide reductase small subunit 2-like protein; p53R2; Ribonucleoside-diphosphate reductase subunit M2 B; ribonucleotide reductase M2 B (TP53 inducible); ribonucleotide reductase regulatory TP53 inducible subunit M2B; RRM2B; TP53-inducible ribonucleotide reductase M2 B
Simboli geni Rrm2b
Specie ospite Rabbit
Immunogeno A synthetic peptide corresponding to a sequence at the C-terminus of human p53R2 (318-332aa EGKTNFFEKRVSEYQ).
Metodo di purificazione Antigen affinity chromatography
Quantità 100 μg
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 299976, 382985, 50484
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Forma Lyophilized
Isotype IgG
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