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Invitrogen™ PAPPA2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Marca: Invitrogen™ PA521046
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Descrizione
A suggested positive control is Hela cell lysate. PA5-21046 can be used with blocking peptide PEP-1160.
PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.
Specifica
| PAPPA2 | |
| Polyclonal | |
| Unconjugated | |
| PAPPA2 | |
| LOC680415; PAPPA2; PAPP-A2; pappalysin 2; pappalysin-2; Pappe; PAPP-E; PLAC3; placenta-specific 3; pregnancy-associated plasma preproprotein-A2; Pregnancy-associated plasma protein A2; Pregnancy-associated plasma protein E1; pregnancy-associated plasma protein-E; RP4-774I24.1; similar to pappalysin 2 isoform 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 23850, 60676, 680415 | |
| Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C | |
| Liquid |
| Western Blot, Immunocytochemistry | |
| 1 mg/mL | |
| PBS with 0.02% sodium azide | |
| Q9BXP8 | |
| PAPPA2 | |
| A 15 amino acid peptide near the amino terminus of human PLAC3. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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