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DiscoverX PathHunter™ C2C12 KISS1R β-Arrestin Cell Line

Codice prodotto. 17303299
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Quantità:
2 Vials
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Codice prodotto. Quantità
17303299 2 Vials
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Codice prodotto. 17303299 Fornitore DiscoverX N. del fornitore 930504C7

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ C2C12 KISS1R β-Arrestin Cell Line measures KISS1R (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ KISS1R β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. [ligand]) based activation of KISS1R GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged KISS1R and EA-tagged β-Arrestin 2. Activation of KISS1R stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry β-Arrestin recruitment
Linea cellulare C2C12
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Kisspeptin-10
Quantità 2 Vials
Target Entry KISS1R
Numero di accesso NM_032551
Titolo del prodotto
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