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DiscoverX PathHunter™ CHO-K1 cyno MRGPRX2 β-Arrestin Cell Line

Codice prodotto. 17334409
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17334409 2 Vials 2 fiale
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Codice prodotto. 17334409 Fornitore DiscoverX N. del fornitore 931134C2

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ CHO-K1 cyno MRGPRX2 β-Arrestin Cell Line measures cMRGPRX2 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells. Cyno protein.

The PathHunter™ cMRGPRX2 β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. PAMP-20) based activation of cMRGPRX2 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged cMRGPRX2 and EA-tagged β-Arrestin 2. Activation of cMRGPRX2 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the Cyno version of the protein.

Specifica

Assay Entry β-Arrestin Recruitment
Linea cellulare CHO-K1
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Cortistatin 14, Human
Quantità 2 Vials
Target Entry cMRGPRX2
Numero di accesso XM_015435307.1
Titolo del prodotto
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