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DiscoverX PathHunter™ CHO-K1 GPR26 β-Arrestin Orphan GPCR Cell Line

Codice prodotto. 17383099
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Quantità:
2 Vials
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Codice prodotto. Quantità
17383099 2 Vials
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Codice prodotto. 17383099 Fornitore DiscoverX N. del fornitore 930392C2A

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ CHO-K1 GPR26 β-Arrestin Orphan GPCR Cell Line measures GPR26 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ GPR26 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR26 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged GPR26 and EA-tagged β-Arrestin 2. Activation of GPR26 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Orphan receptor with unknown ligand.

Specifica

Assay Entry β-Arrestin recruitment
Linea cellulare CHO-K1
Da utilizzare con (applicazione) Cell Lines
Quantità 2 Vials
Target Entry GPR26
Numero di accesso NM_153442
Titolo del prodotto
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