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DiscoverX PathHunter™ CHO-K1 GPR39 β-Arrestin Orphan GPCR Cell Line

Codice prodotto. 17363009
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17363009 2 Vials 2 fiale
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Codice prodotto. 17363009 Fornitore DiscoverX N. del fornitore 930338C2

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descripción

The PathHunter™ CHO-K1 GPR39 β-Arrestin Orphan GPCR Cell Line measures GPR39 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ GPR39 cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of GPR39 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged GPR39 and EA-tagged β-Arrestin 2. Activation of GPR39 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Orphan receptor with unknown ligand.

Especificaciones

Assay Entry β-Arrestin recruitment
Linea cellulare CHO-K1
Formato 2 vials
Da utilizzare con (applicazione) Cell Lines
Quantità 2 Vials
Target Entry GPR39
Numero di accesso NM_001508
Título del producto
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