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DiscoverX PathHunter™ CHO-K1 P2RY4 β-Arrestin Cell Line

Codice prodotto. 17382859
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Quantità:
2 Vials
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Codice prodotto. Quantità
17382859 2 Vials
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Codice prodotto. 17382859 Fornitore DiscoverX N. del fornitore 930263C2

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ CHO-K1 P2RY4 β-Arrestin Cell Line measures P2RY4 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ P2RY4 β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. UTP) based activation of P2RY4 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged P2RY4 and EA-tagged β-Arrestin 2. Activation of P2RY4 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Linea cellulare CHO-K1
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Uridine 5'-Triphosphate
Quantità 2 Vials
Target Entry P2RY4
Numero di accesso NM_002565
Titolo del prodotto
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