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DiscoverX PathHunter™ CHO-K1 PTGIR β-Arrestin Cell Line

Codice prodotto. 17362939
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Quantità:
2 Vials
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Codice prodotto. Quantità
17362939 2 Vials
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Codice prodotto. 17362939 Fornitore DiscoverX N. del fornitore 930305C2

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descripción

The PathHunter™ CHO-K1 PTGIR β-Arrestin Cell Line measures PTGIR (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ PTGIR β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostagladin I2, beraprost) based activation of PTGIR GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged PTGIR and EA-tagged β-Arrestin 2. Activation of PTGIR stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Especificaciones

Assay Entry β-Arrestin recruitment
Linea cellulare CHO-K1
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Beraprost
Quantità 2 Vials
Target Entry PTGIR
Numero di accesso AY242134
Título del producto
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