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DiscoverX PathHunter™ CHO-K1 rDRD2S (Short Isoform) β-Arrestin Cell Line

Codice prodotto. 17383799
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17383799 2 Vials 2 fiale
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Codice prodotto. 17383799 Fornitore DiscoverX N. del fornitore 930778C2

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ CHO-K1 rDRD2S (Short Isoform) β-Arrestin Cell Line measures rDRD2S (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells. Rat protein.

The PathHunter™ rDRD2S β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dopamine) based activation of rDRD2S GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged rDRD2S and EA-tagged β-Arrestin 2. Activation of rDRD2S stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells. Please note that this product expresses the rat version of this protein.

Specifica

Assay Entry β-Arrestin Recruitment
Linea cellulare CHO-K1
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Pergolide mesylate salt
Quantità 2 Vials
Target Entry rDRD2S
Numero di accesso M36831
Titolo del prodotto
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