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DiscoverX PathHunter™ eXpress EphB1 Functional Assay

Codice prodotto. 17393969
Encompass
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Quantità:
200 dp (2 x 96-well)
Dimensione della confezione:
1 set
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Codice prodotto. Quantità unitSize
17393969 200 dp (2 x 96-well) 1 set
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Codice prodotto. 17393969 Fornitore DiscoverX N. del fornitore 930893E3CP16M

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

The PathHunter™ eXpress EphB1 Functional Assay measures EphB1 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. eXpress kits contain all assay materials: cells, reagents, and plates.

The PathHunter™ eXpress EphB1 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphB1 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cells overexpress PK-tagged EphB1 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates.

Specifica

Assay Entry Receptor Phosphorylation
Da utilizzare con (applicazione) Assay-Ready eXpress Kits
Primary Agonist Recombinant Mouse Ephrin-B2Fc Chimera, CF
Quantità 200 dp (2 x 96-well)
Target Entry EphB1
Linea cellulare U2OS
Bersaglio EphB1
Titolo del prodotto
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