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DiscoverX PathHunter™ eXpress mGIPR U2OS β-Arrestin GPCR Assay

Codice prodotto. 17363889
Encompass
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Quantità:
1,000 dp (10 x 96-well)
Dimensione della confezione:
1 set
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Codice prodotto. Quantità unitSize
17363889 1,000 dp (10 x 96-well) 1 set
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Codice prodotto. 17363889 Fornitore DiscoverX N. del fornitore 930846E3MCP5L

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Descrizione

The PathHunter™ eXpress mGIPR U2OS β-Arrestin GPCR Assay measures mGIPR (GPCR) activity via recruitment of β-Arrestin2. eXpress kits contain all assay materials: cells, reagents, and plates. Mouse version.

The PathHunter™ mGIPR β-Arrestin eXpress Kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. GIP) based activation of mGIPR GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cells overexpress PK-tagged mGIPR and EA-tagged β-Arrestin 2. Activation of mGIPR stimulates the recruitment of β-Arrestin 2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. Please note that this product expresses the Mouse version of this protein.

Specifica

Assay Entry GPCR
Da utilizzare con (applicazione) Assay-Ready eXpress Kits
Quantità 1,000 dp (10 x 96-well)
Target Entry mGIPR
Linea cellulare U2OS
Bersaglio mGIPR
Titolo del prodotto
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