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DiscoverX PathHunter™ U2OS EphA4 Functional Assay

Codice prodotto. 17373939
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17373939 2 Vials 2 fiale
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Codice prodotto. 17373939 Fornitore DiscoverX N. del fornitore 930877C3

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Descrizione

The PathHunter™ U2OS EphA4 Functional Assay measures EphA4 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS EphA4 Functional Assay provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting RTKs. This kit assesses RTK activation via detection of activated EphA4 dimerization-induced SH2 domain protein recruitment. This product uses EFC technology. The included cell line overexpresses PK-tagged EphA4 and an EA-tagged SH2 domain protein. Upon ligand-induced receptor activation, SH2-EA recruitment leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry U2OS
Linea cellulare U2OS
Da utilizzare con (applicazione) Cell Lines
Primary Agonist EphrinA3
Quantità 2 Vials
Target Entry EphA4
Numero di accesso NM_004438.3
Produkttitel
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