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DiscoverX PathHunter™ U2OS OPRK1 β-Arrestin Cell Line

Codice prodotto. 17382789
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Quantità:
2 Vials
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Codice prodotto. Quantità
17382789 2 Vials
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Codice prodotto. 17382789 Fornitore DiscoverX N. del fornitore 930234C3

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ U2OS OPRK1 β-Arrestin Cell Line measures OPRK1 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ OPRK1 β-Arrestin cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. dynorphin A) based activation of OPRK1 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged OPRK1 and EA-tagged β-Arrestin 2. Activation of OPRK1 stimulates the recruitment of β-Arrestin 2 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Linea cellulare U2OS
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Dynorphin A
Quantità 2 Vials
Target Entry OPRK1
Numero di accesso AF498922
Titolo del prodotto
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