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DiscoverX PathHunter™ U2OS OPRM1 β-Arrestin-1 Cell Line

Codice prodotto. 17383939
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17383939 2 Vials 2 fiale
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Codice prodotto. 17383939 Fornitore DiscoverX N. del fornitore 930878C3

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ U2OS OPRM1 β-Arrestin-1 Cell Line measures OPRM1 (GPCR) activity via recruitment of β-Arrestin-1. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ OPRM1 (ARR1) cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. met 5-enkephalin) based activation of OPRM1 GPCR activity via detection of β-arrestin recruitment. This product uses EFC technology (www.discoverx.com/technologies-platforms/enzyme-fragment-complementation-technology). The included cell line overexpresses PK-tagged OPRM1 and EA-tagged β-Arrestin-1. Activation of OPRM1 stimulates the recruitment of β-Arrestin-1 and produces EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry β-Arrestin Recruitment
Linea cellulare U2OS
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Met 5-Enkephalin
Quantità 2 Vials
Target Entry OPRM1 (ARR1)
Numero di accesso NM_000914.3
Titolo del prodotto
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