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DiscoverX PathHunter™ U2OS PRβ Protein Interaction Cell Line

Codice prodotto. 17323899
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17323899 2 Vials 2 fiale
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Codice prodotto. 17323899 Fornitore DiscoverX N. del fornitore 930851C3

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ U2OS PRβ Protein Interaction Cell Line measures activated PRβ nuclear hormone receptor interaction with SRCPs. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ PRβ Protein Interaction cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting NHR activation and recruitment of cofactors. This cell line enables assessment of ligand (e.g. testosterone, norgestrel) based NHR activation via detection of SRCP (steroid receptor co-activator peptide) recruitment. This product uses EFC technology. The included cell line overexpresses PK-tagged PRβ NHR and EA-tagged steroid receptor co-activator peptide (SRCP). Upon activation of PRβ, induced interaction with SRCP leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry Protein Interaction
Linea cellulare U2OS
Da utilizzare con (applicazione) Cell Lines
Primary Agonist D(-)-Norgestrel
Quantità 2 Vials
Target Entry PRβ
Numero di accesso NM_000926
Titolo del prodotto
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