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DiscoverX PathHunter™ U2OS TORC1 Nuclear Translocation Cell Line

Codice prodotto. 17353869
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17353869 2 Vials 2 fiale
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Codice prodotto. 17353869 Fornitore DiscoverX N. del fornitore 930833C3

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ U2OS TORC1 Nuclear Translocation Cell Line measures CRTC/CREB pathway activation via nuclear translocation of TORC1. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS TORC1 Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the CRTC/CREB pathway. This cell line enables assessment of ligand (e.g. forskolin) based pathway activation via detection of resulting TORC1 (CRTC1) nuclear translocation. This product uses EFC technology. The included cell line overexpresses PL-tagged TORC1 (CRTC1) and nuclear localized EA. Upon pathway activation, induced nuclear translocation of TORC1 leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry TORC1 (CRTC1) nuclear translocation
Linea cellulare U2OS
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Forskolin
Quantità 2 Vials
Target Entry TORC1 (CRTC1)
Numero di accesso NM_015321.1
Titolo del prodotto
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