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DiscoverX PathHunter™ U2OS XBP1 Nuclear Translocation Cell Line

Codice prodotto. 17323909
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Quantità:
2 Vials
Dimensione della confezione:
2 fiale
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Codice prodotto. Quantità unitSize
17323909 2 Vials 2 fiale
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Codice prodotto. 17323909 Fornitore DiscoverX N. del fornitore 930857C3

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Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ U2OS XBP1 Nuclear Translocation Cell Line measures IRE1-XBP1 pathway activation via nuclear translocation of XBP1. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ U2OS XBP1 Nuclear Translocation Cell Line is a stable, engineered cell line for use in studying drug candidates affecting the IRE1/XBP1 pathway. This cell line enables assessment of ligand (e.g. thapsigargin) based pathway activation via detection of resulting XBP1 nuclear translocation. This product uses EFC technology. The included cell line overexpresses PL-tagged XBP1 and nuclear localized EA. Upon pathway activation, induced nuclear translocation of XBP1 leads to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry XBP1 nuclear translocation
Linea cellulare U2OS
Da utilizzare con (applicazione) Cell Lines
Primary Agonist Thapsigargin
Quantità 2 Vials
Target Entry XBP1
Numero di accesso BC012841
Titolo del prodotto
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