missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Cell Lines and Blood Products
  4. Cell Lines and Cell Cultures
  5. General Cell Lines and Cell Cultures
  6. 17353739

DiscoverX PathHunter™ VIPR1 Activated GPCR Internalization U2OS Cell Line

Codice prodotto. 17353739
Encompass
Cambia vista
Click to view available options
Quantità:
2 Vials
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Codice prodotto. Quantità
17353739 2 Vials
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso
Codice prodotto. 17353739 Fornitore DiscoverX N. del fornitore 930739C3

Please to purchase this item. Need a web account? Register with us today!

Les retours ne sont pas autorisés pour ce produit. Consulta la politica di reso

Descrizione

The PathHunter™ VIPR1 Activated GPCR Internalization U2OS Cell Line measures VIPR1 (GPCR) internalization via early-endosome localization. This cell line ships as two vials of cryopreserved cells.

The PathHunter™ VIPR1 Activated GPCR internalization cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) affecting GPCR activation and internalization. This cell line enables assessment of ligand (e.g. VIP) based internalization of VIPR1 via detection of localization to the early endosome. This product uses EFC technology. The included cell line overexpresses EA-tagged β-arrestin 2 as well as a PK-tagged early endosome protein and untagged VIPR1. Upon ligand-induced receptor activation, β-arrestin 2 is recruited to the activated GPCR and the resulting VIPR1-arrestin complex is internalized to the early endosome, leading to production of EFC signal. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifica

Assay Entry Receptor Internalization
Linea cellulare U2OS
Da utilizzare con (applicazione) Cell Lines
Primary Agonist VIP, Human
Quantità 2 Vials
Target Entry VIPR1
Numero di accesso NM_004624
Titolo del prodotto
Selezionare un problema

Facendo clic su Invia, l'utente riconosce che potrebbe essere contattato da Fisher Scientific in merito al feedback fornito in questo modulo. Non condivideremo le vostre informazioni per altri scopi. Tutte le informazioni di contatto fornite saranno conservate in conformità con la nostra Politica sulla privacy. Informativa sulla privacy.