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Invitrogen™ Phospho-MECP2 (Ser421) Polyclonal Antibody
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Codice prodotto. 15378154
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Quantità:
100 μL
Dimensione della confezione:
100µL
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Codice prodotto. Quantità unitSize
15378154 100 μL 100µL
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Codice prodotto. 15378154 Fornitore Invitrogen™ N. del fornitore PA535396

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Descrizione

Rabbit Polyclonal Antibody

This antibody is predicted to react with human and non-human primate based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots.

MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain. MECP2 is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MECP2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
TRUSTED_SUSTAINABILITY

Specifica

Antigene Phospho-MECP2 (Ser421)
Applicazioni Western Blot
Classificazione Polyclonal
Concentrazione 0.25 mg/mL
Coniugato Unconjugated
Formulazione 0.01M HEPES with 0.1mg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
Gene Mecp2
N. accesso geni Q00566, Q9Z2D6
Alias gene 1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
Simboli geni Mecp2
Specie ospite Rabbit
Immunogeno Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 of mouse MeCP2 conjugated to KLH.
Metodo di purificazione Affinity chromatography
Quantità 100 μL
Status giuridico RUO
Primario o secondario Primary
ID gene (immissione) 17257, 29386
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Forma Liquid
Isotype IgG
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